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Dr. Md. Abdul  Hannan
Dr. Md. Abdul Hannan

Professor Contact No : +821096756054 (South Korea)
Department of Biochemistry and Molecular Biology Email : hannanbmb@bau.edu.bd
Faculty of Agriculture ResearchGate Google Scholar
Research Interest:    Phytochemical screening of medicinal plants from marine and terrestrial origins for neurotrophic and neuroprotective substances Medicinal chemistry. Functional foods for lifestyle diseases. 
PhD In Biotechnology    - 2013
Pukyong National University
South Korea
MS In Biochemistry    - 2007
Bangladesh Agricultural University
Doctor Of Veterinary Medicine (DVM)    - 2004
Bangladesh Agricultural University
Total Number:  4

1. Phytochemical screening of natural products from marine and terrestrial plants for neurotrophic activity.

2. Isolation and purification of active ingredients from indigenous herbal plants and their subsequent incorporation in wheat based food shown to have positive impact in reducing blood glucose and cholesterol level in diabetic subjects.

3. Uplifting of nutritional qualities of existing and newly developed varieties of wheat in order to develop low-cost as well as vitamin and mineral supplemented wheat based food for diabetic patients.

4. Development of balanced and complete therapeutic foods with low doses of semipurified antidiabetic and cholesterol lowering principles. These foods reduce in large part the needs for chemical drugs which often have serious side effects. Besides the formulated foods presented in powdered form or as whole grain mixture that can be consumed as bread, cake (pitha), broth soup, boiled form etc.

Total Number:  6

(a)  Attended a course on “Data Analysis: Excel and Mstatc” from July 09 to 21, 2005 organized by the Graduate Training Institute (GTI), Bangladesh Agricultural University, Mymensingh.

(b)  Attended an advanced course on “Communicative English” from April 10 to May 25, 2005 (40 contact hours) arranged by the Department of Languages, Bangladesh Agricultural University, Mymensingh.

(c)   Attended a course on “Scientific Report Writing” from May 20 to 25, 2006 organized by the Graduate Training Institute (GTI), Bangladesh Agricultural University, Mymensingh.

(d)  Attended intensive training on “Korean Language Course” in Korean Language Education Center, Silla University, Busan, South Korea as 2009 Korean Government Scholarship Program Student from September 1, 2009 to August 6, 2010.

(e)  Attended “Foundation Training for University Teachers” from August 25 to September 26, 2013, organized by the Graduate Training Institute (GTI), Bangladesh Agricultural University, Mymensingh.

(f) Attended training on “Integrated Approaches to Food Security” under NICHE-BGD-156 Project of Interdisciplinary Centre for Food Security (ICF), BAU, Mymensingh during 16.10.2017 - 27.10.2017 at Wageningen University & Research, the Netherlands.

27 Jul, 2005 - 26 Jul, 2007
Assistant Professor
27 Jul, 2007 - 22 Aug, 2013
Associate Professor
23 Aug, 2013 - 22 Aug, 2017
23 Aug, 2018 -
Total Number:  51
  1. Rahman, M., Hannan, M.A., Dash, R., Rahman, M.D., Islam, R., Uddin, M.J., Sohag, A.A.M. and Rhim, H., 2021. Phytochemicals as a complement to cancer chemotherapy: pharmacological modulation of autophagy-apoptosis pathway. Frontiers in Pharmacology12, p.718. 10.3389/fphar.2021.639628
  2. Rahman, M.A., Dash, R., Sohag, A.A.M., Alam, M., Rhim, H., Ha, H., Moon, I.S., Uddin, M.J. and Hannan, M.A., 2021. Prospects of Marine Sterols against Pathobiology of Alzheimer’s Disease: Pharmacological Insights and Technological Advances. Marine Drugs19(3), p.167.  https://doi.org/10.3390/md19030167
  3. Dash, R., Jahan, I., Ali, M.C., Mitra, S., Munni, Y.A., Timalsina, B., Hannan, M.A. and Moon, I.S. (2021). Potential roles of natural products in the targeting of proteinopathic neurodegenerative diseases. Neurochemistry International, p.105011. https://doi.org/10.1016/j.neuint.2021.105011
  4. Uddin, M. J., Kim, E. H., Hannan, M. A., & Ha, H. (2021). Pharmacotherapy against Oxidative Stress in Chronic Kidney Disease: Promising Small Molecule Natural Products Targeting Nrf2-HO-1 Signaling. Antioxidants, 10(2), 258. https://doi.org/10.3390/antiox10020258
  5. Hossain, M. T., Sohag, A. A. M., Haque, M. N., Tahjib-Ul-Arif, M., Dash, R., Chowdhury, M. T. H., ... & Hannan, M. A. (2021). Nutritional Value, Phytochemical Profile, Antioxidant Property and Agar Yielding Potential of Macroalgae from Coasts of Cox’s Bazar and St. Martin’s Island of Bangladesh. Journal of Aquatic Food Product Technology, 1-11. https://doi.org/10.1080/10498850.2020.1869876
  6. Hannan, M. A., Haque, M. N., Munni, Y. A., Oktaviani, D. F., Timalsina, B., Dash, R., ... & Moon, I. S. (2021). Centella asiatica promotes early differentiation, axodendritic maturation and synaptic formation in primary hippocampal neurons. Neurochemistry International, 144, 104957. https://doi.org/10.1016/j.neuint.2021.104957
  7. Haque, M. N., Hannan, M. A., Dash, R., Choi, S. M., & Moon, I. S. (2020). The potential LXRβ agonist stigmasterol protects against hypoxia/reoxygenation injury by modulating mitophagy in primary hippocampal neurons. Phytomedicine, 153415. https://doi.org/10.1016/j.phymed.2020.153415
  8. Dash, R., Ali, M. C., Jahan, I., Munni, Y. A., Mitra, S., Hannan, M. A., Timalsina, B., Oktaviani, D.F., Choi, H.J. & Moon, I. S. (2020). Emerging potential of cannabidiol in reversing proteinopathies. Ageing Research Reviews, 101209. https://doi.org/10.1016/j.arr.2020.101209
  9. Rahman, M. A., Rahman, M. H., Biswas, P., Hossain, M. S., Islam, R., Hannan, M. A., Uddin, M. J. & Rhim, H. (2021). Potential therapeutic role of phytochemicals to mitigate mitochondrial dysfunctions in Alzheimer’s disease. Antioxidants, 10(1), 23. https://doi.org/10.3390/antiox10010023
  10. Hossain, K.S., Hossain, M.G., Moni, A., Rahman, M.M., Rahman, U.H., Alam, M., Kundu, S., Rahman, M.M., Hannan, M.A. & Uddin, M.J. (2020). Prospects of honey in fighting against COVID-19: pharmacological insights and therapeutic promises. Heliyon, 6(12), e05798. https://doi.org/10.1016/j.heliyon.2020.e05798
  11. Farjana, M., Moni, A., Sohag, A.A.M., Hasan, A., Hannan, M.A., Hossain, M.G. and Uddin, M.J. (2020). Repositioning vitamin C as a promising option to alleviate complications associated with COVID-19. Infection & Chemotherapy, 52(4), p.461. https://doi.org/10.3947/ic.2020.52.4.461
  12. Dash, R., Ali, M., Rana, M., Munni, Y.A., Barua, L., Jahan, I., Haque, M., Hannan, M. A., and Moon, I.S. (2020). Computational SNP Analysis and Molecular Simulation Revealed the Most Deleterious Missense Variants in the NBD1 Domain of Human ABCA1 Transporter. International journal of molecular sciences21(20), p.7606. https://doi.org/10.3390/ijms21207606
  13. Islam, M. N., Hossain, K. S., Sarker, P. P., Ferdous, J., Hannan, M. A., Rahman, M. M., ... & Uddin, M. J. (2020). Revisiting pharmacological potentials of Nigella sativa seed: a promising option for COVID-19 prevention and cure. Phytotherapy Research. 2020;116. https://doi.org/10.1002/ptr.6895
  14. Hannan, M. A., Dash, R., Haque, M. N., Choi, S. M., & Moon, I. S. (2020). Integrated system pharmacology and in silico analysis elucidate neuropharmacological actions of Withania somnifera in the treatment of Alzheimer's disease. CNS Neurol Disord Drug Targets. https://doi.org/10.2174/1871527319999200730214807
  15. Dash, R., Mitra, S., Ali, M. C., Oktaviani, D. F., Hannan, M. A., Choi, S. M., & Moon, I. S. (2020). Phytosterols: Targeting Neuroinflammation in Neurodegeneration. Curr Pharm Des. https://doi.org/10.2174/1381612826666200628022812
  16. Hannan, M. A., Dash, R., Haque, M. N., Mohibbullah, M., Sohag, A. A. M., Rahman, M. A., . . . Moon, I. S. (2020). Neuroprotective Potentials of Marine Algae and Their Bioactive Metabolites: Pharmacological Insights and Therapeutic Advances. Mar Drugs, 18(7). https://doi.org/10.3390/md18070347
  17. Hannan, M. A., Rahman, M. A., Rahman, M. S., Sohag, A. A. M., Dash, R., Hossain, K. S., . . . Uddin, M. J. (2020). Intermittent fasting, a possible priming tool for host defense against SARS-CoV-2 infection: Crosstalk among calorie restriction, autophagy and immune response. Immunol Lett, 226, 38-45. https://doi.org/10.1016/j.imlet.2020.07.001
  18. Sohag, A. A. M., Hannan, M. A., Rahman, S., Hossain, M., Hasan, M., Khan, M. K., . . . Uddin, M. J. (2020). Revisiting potential druggable targets against SARS-CoV-2 and repurposing therapeutics under preclinical study and clinical trials: A comprehensive review. Drug Development Research 81(8): 919-941. https://doi.org/10.1002/ddr.21709
  19. Hannan, M. A., Islam, M. N., & Uddin, M. J. (2020). Self-confidence as an immune-modifying psychotherapeutic intervention for COVID-19 patients and understanding of its connection to CNS-endocrine-immune axis. J Adv Biotechnol Exp Ther3, 14-7. https://doi.org/10.5455/jabet.2020.d151
  20. Hannan, M. A., Dash, R., Sohag, A. A. M., Haque, M. N., & Moon, I. S. (2020). Neuroprotection Against Oxidative Stress: Phytochemicals Targeting TrkB Signaling and the Nrf2-ARE Antioxidant System. Front Mol Neurosci, 13, 116. https://doi.org/10.3389/fnmol.2020.00116
  21. Hannan, M. A., Haque, M. N., Mohibbullah, M., Dash, R., Hong, Y. K., & Moon, I. S. (2020). Gelidium amansii Attenuates Hypoxia/Reoxygenation-Induced Oxidative Injury in Primary Hippocampal Neurons through Suppressing GluN2B Expression. Antioxidants (Basel), 9(3). https://dx.doi.org/10.3390%2Fantiox9030223
  22. Hannan, M. A., Sohag, A. A. M., Dash, R., Haque, M. N., Mohibbullah, M., Oktaviani, D. F., . . . Moon, I. S. (2020). Phytosterols of marine algae: Insights into the potential health benefits and molecular pharmacology. Phytomedicine, 69, 153201. https://doi.org/10.1016/j.phymed.2020.153201
  23. Sohag, A. A. M., Tahjib-Ul-Arif, M., Afrin, S., Khan, M. K., Hannan, M. A., Skalicky, M., . . . Murata, Y. (2020). Insights into nitric oxide-mediated water balance, antioxidant defence and mineral homeostasis in rice (Oryza sativa L.) under chilling stress. Nitric Oxide, 100-101, 7-16. https://doi.org/10.1016/j.niox.2020.04.001
  24. Dash, R., Ali, M. C., Dash, N., Azad, M. A. K., Hosen, S. M. Z., Hannan, M. A., & Moon, I. S. (2019). Structural and Dynamic Characterizations Highlight the Deleterious Role of SULT1A1 R213H Polymorphism in Substrate Binding. Int J Mol Sci, 20(24). https://dx.doi.org/10.3390%2Fijms20246256
  25. Dash, R., Arifuzzaman, M., Mitra, S., Hannan, M. A., Absar, N., & Hosen, S. M. Z. (2019). Unveiling the Structural Insights into the Selective Inhibition of Protein Kinase D1. Curr Pharm Des, 25(10), 1059-1074. https://doi.org/10.2174/1381612825666190527095510
  26. Hannan, M. A., Dash, R., Sohag, A. A. M., & Moon, I. S. (2019). Deciphering Molecular Mechanism of the Neuropharmacological Action of Fucosterol through Integrated System Pharmacology and In Silico Analysis. Mar Drugs, 17(11). https://dx.doi.org/10.3390%2Fmd17110639
  27. Hannan, M. A., Haque, M. N., Dash, R., Alam, M., & Moon, I. S. (2019). 3β, 6β-dichloro-5-hydroxy-5α-cholestane facilitates neuronal development through modulating TrkA signaling regulated proteins in primary hippocampal neuron. Sci Rep, 9(1), 18919. https://doi.org/10.1038/s41598-019-55364-8
  28. Hannan, M. A., Mohibbullah, M., Hong, Y. K., & Moon, I. S. (2017). Proteomic Analysis of the Neurotrophic Effect of Gelidium amansii in Primary Cultured Neurons. J Med Food, 20(3), 279-287. https://doi.org/10.1089/jmf.2016.3848
  29. Mohibbullah, M., Hannan, M. A., Park, I. S., Moon, I. S., & Hong, Y. K. (2016). The Edible Red Seaweed Gracilariopsis chorda Promotes Axodendritic Architectural Complexity in Hippocampal Neurons. J Med Food, 19(7), 638-644. https://doi.org/10.1089/jmf.2016.3694
  30. Mohibbullah, M., Bhuiyan, M. M., Hannan, M. A., Getachew, P., Hong, Y. K., Choi, J. S., . . . Moon, I. S. (2016). The Edible Red Alga Porphyra yezoensis Promotes Neuronal Survival and Cytoarchitecture in Primary Hippocampal Neurons. Cell Mol Neurobiol, 36(5), 669-682. https://doi.org/10.1007/s10571-015-0247-x
  31. Mohibbullah, M., Hannan, M. A., Choi, J. Y., Bhuiyan, M. M., Hong, Y. K., Choi, J. S., . . . Moon, I. S. (2015). The Edible Marine Alga Gracilariopsis chorda Alleviates Hypoxia/Reoxygenation-Induced Oxidative Stress in Cultured Hippocampal Neurons. J Med Food, 18(9), 960-971. https://doi.org/10.1089/jmf.2014.3369
  32. Haque Bhuiyan, M. M., Mohibbullah, M., Hannan, M. A., Hong, Y. K., Han, C. H., Kim, Y. K., & Moon, I. S. (2015). The neuritogenic and synaptogenic effects of the ethanolic extract of radix Puerariae in cultured rat hippocampal neurons. J Ethnopharmacol, 173, 172-182. https://doi.org/10.1016/j.jep.2015.07.013
  33. Maqueshudul Haque Bhuiyan, M., Mohibbullah, M., Hannan, M. A., Hong, Y. K., Choi, J. S., Choi, I. S., & Moon, I. S. (2015). Undaria pinnatifida Promotes Spinogenesis and Synaptogenesis and Potentiates Functional Presynaptic Plasticity in Hippocampal Neurons. Am J Chin Med, 43(3), 529-542. https://doi.org/10.1142/s0192415x15500330
  34. Wares, M.A., Awal, M.A., Das, S.K., Hannan, M.A., Anas, M.A., Latif, M.A. and Masud, N., 2015. Chronic natural arsenic exposure affecting histoarchitecture of gonads in Black Bengal goats (Capra aegagrushircus). Journal of Advanced Veterinary and Animal Research, 2(2), pp.128-133. http://dx.doi.org/10.5455/javar.2015.b61
  35. Hannan, M. A., Kang, J. Y., Mohibbullah, M., Hong, Y. K., Lee, H., Choi, J. S., . . . Moon, I. S. (2014). Moringa oleifera with promising neuronal survival and neurite outgrowth promoting potentials. J Ethnopharmacol, 152(1), 142-150. https://doi.org/10.1016/j.jep.2013.12.036
  36. Hannan, M. A., Mohibbullah, M., Hong, Y. K., Nam, J. H., & Moon, I. S. (2014). Gelidium amansii promotes dendritic spine morphology and synaptogenesis, and modulates NMDA receptor-mediated postsynaptic current. In Vitro Cell Dev Biol Anim, 50(5), 445-452. https://doi.org/10.1007/s11626-013-9721-2
  37. Hannan, M. A., Mohibbullah, M., Hwang, S. Y., Lee, K., Kim, Y. C., Hong, Y. K., & Moon, I. S. (2014). Differential neuritogenic activities of two edible brown macroalgae, Undaria pinnatifida and Saccharina japonica. Am J Chin Med, 42(6), 1371-1384. https://doi.org/10.1142/s0192415x14500864
  38. Getachew, P., Hannan, M.A., Nam, B.H., Cho, J.Y. and Hong, Y.K., 2014. Induced changes in the proteomic profile of the phaeophyte Saccharina japonica upon colonization by the bryozoan Membranipora membranacea. Journal of applied phycology26(1), pp.657-664. https://doi.org/10.1007/s10811-013-0105-5
  39. Talukder, S., Sarker, S., Hossain, M.A., Khan, M.A.H., Hannan, M.A. and Islam, M.T., 2012. Evaluation of fertility disrupting potentials of Abrus precatorius seed extracts in male rats for arresting spermatogenesis and suppressed fertility in vivo. Pakistan Veterinary Journal34(1), pp.18-23. http://pvj.com.pk/pdf-files/34_1/18-23.pdf
  40. Hannan, A., Kang, J. Y., Hong, Y. K., Lee, H., Choi, J. S., Choi, I. S., & Moon, I. S. (2013). The marine alga Gelidium amansii promotes the development and complexity of neuronal cytoarchitecture. Phytother Res, 27(1), 21-29. https://doi.org/10.1002/ptr.4684
  41. Hannan, M. A., Kang, J. Y., Hong, Y. K., Lee, H., Chowdhury, M. T., Choi, J. S., . . . Moon, I. S. (2012). A brown alga Sargassum fulvellum facilitates neuronal maturation and synaptogenesis. In Vitro Cell Dev Biol Anim, 48(8), 535-544. https://doi.org/10.1007/s11626-012-9537-5
  42. Hannan, M.A, Hossain, M.A. and Islam, M.T., 2010. Seed extracts of a Bangladeshi medicinal plant Abrus precatorius show antifertility activity in female rats. Oriental Pharmacy and Experimental Medicine, 10, pp.103-110. https://doi.org/10.3742/OPEM.2010.10.2.103
  43. Mortuza, M.G., Hannan, M.A. and Tzen, J.T., 2009. Chemical composition and functional properties of Vicia faba L. from Bangladesh. Bangladesh Journal of Botany, 38(1), pp.93-97. https://doi.org/10.3329/bjb.v38i1.5129
  44. Noor, T.A., Hossain, M.A., Chowdhury, M.A.K., Hannan, M.A. and Islam, M.S., 2009. Effect of varying levels of nitrogen and cowdung on yield and yield attributes of an aromatic rice cv. Kalizira. International Journal of BioResearch, 6(5), pp.72-76.
  45. Islam, M.S., Hossain, M.A., Chowdhury, M.A.H. and Hannan, M.A., 2008. Effect of nitrogen and transplanting date on yield and yield components of aromatic rice. Journal of the Bangladesh Agricultural University, 6(2), pp.291-296. DOI: 10.3329/jbau.v6i2.4824
  46. Sarker, M.A.S., Siddiqua, A., Hannan, M.A. and Hossain. M.A., 2008. Effect of processing on nutrient compositions, functional properties and cooking quality of some selected chickpea (Cicer arietinum L.) varieties. Bangladesh Journal of Progressive Science and Technology, 6(2), pp.309-312.
  47. Mahmoad, M.F., Awal,M.A., Hannan, M.A. and Islam, M.R., 2008. Histopathological and Biochemical studies of induced lead acetate toxicity in rats. Bangladesh Journal of Progressive Science and Technology, 6(1), pp.153-156.
  48. Hossain. M.A., Hannan, M.A., Talukder, N.M. and Hanif, M.A., 2008. Effect of different rates and methods of zinc application on the yield and nutritional qualities of rice cv. BR11. Journal of Agroforestry and Environment, 2(1), pp.117-121.
  49. Rahman, M.S., Rashid, M.H., Hannan, M.A. and Ahmed, S., 2007. Screening for natural antioxidant from plant origin. Bangladesh Journal of Progressive Science and Technology, 5(1), pp.85-88.
  50. Hossain, M.A., Zaman, M.B., Hannan, M.A. and Hossain, M.T., 2006. Antidiabetic effect of cinnamon (Cinnamon zealanicum) bark extracts on streptozotocin-induced diabetic rats. Bangladesh Veterinarian, 23 (1), pp.53-58.
  51. Hannan, M.A., Hossain, M.A., Islam, M.T. and Chowdhury, E.H., 2006. Contraceptive effects of Abrus precatorius seed on female rats. J. Bangladesh Soc. Agric. Sci. Technol, 3(3&4), pp.185-188.
Total Number:  8
  1. Poster paper titled ‘Neurotrophic effect of Gelidiumamansiiin primary cultured neurons: revealing molecular mechanism by proteomic approach’ presented in “KSBMB International Conference 2019” held from June 2 to 5, 2019 at ICC, Jeju, Korea.
  2. Poster paper titled ‘Neurotrophic potentials of Moringa oleifera in hippocampal neurons
    ’ presented in “KSBMB International Conference 2019” held from June 2 to 5, 2019 at ICC, Jeju, Korea.
  3. Oral paper titled ‘Marine algae as a potential source of neurotrophic substances’ presented in “53rd  Annual Meeting and International Symposium of Korean Society of Life Science” held from October 25 to 26, 2012 at Kyunpook National University, Daegu, Korea.
  4.  Poster paper titled ‘Neurotrophic potentials of Undaria pinnatifida’ presented in “53rd  Annual Meeting and International Symposium of Korean Society of Life Science” held from October 25 to 26, 2012 at Kyunpook National University, Daegu, Korea.
  5.  Poster paper titled ‘The effect of marine natural sources on promoting early neuronal neurite outgrowth and dendritic arborization’ presented in “52nd Annual General Meeting and International Conference of Korean Society of Life Science” held from October 27 to 28, 2011 at Bexco, Busan, Korea.
  6. Poster paper titled ‘Potential effect of marine natural resources on promoting early neurite outgrowth and arborization in cultured neurons’ presented in BISFE’2011 at Bexco, Busan, Korea.
  7. Poster paper titled ‘Screening of marine algae for neurotrophic activity’ presented in “51st Annual General Meeting and International Conference of Korean Society of Life Science” at Jeonju, Korea.
  8. Oral Paper titled ‘Seed extracts of a Bangladeshi medicinal plant Abrus precatorius L. show antifertility activity in female rats’ presented in “Euro-India First International Conference On Holistic Medicine-2008” held from August 21 to 23, 2008 at Kottayam, Kerala, India.
No patent information available..
Title Institution Subject Receipt Date
Korea Research Fellowship Dongguk University College of Medicine Molecular Neurobiology 2018
Korean Government Scholarship Pukyong National University Biotechnology 2009
Prof. Dr. Abdul Karim Memorial Prize Bangladesh Agricultural University Biochemistry 2010
Membership Type Organization
Member Korean Society of Biochemistry and Molecular Biology